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Home > Nutrition > Are Guava Leaves Poisonous?

Are Guava Leaves Poisonous?

February 10, 2023
5 min read
By Shiza Khan, M.Sc. – Clinical Nutrition & Dietetics | Dietitian/Nutritionist

In this article:

  • Uses of Guava Leaves
  • How to Consume
  • How Many Guava Leaves can I Give My Child for Diarrhea?
  • Final Word

Guava is a tropical fruit famous for its high vitamin C content. But did you know its leaves have medicinal properties?

are guava leaves poisonous to health?

Various countries around the world make use of guava leaves to make decoctions, poultices, infusions, and teas to treat and manage various health conditions.

Yes! Not only are guava leaves nonpoisonous, but they also offer a variety of health benefits.

Uses of Guava Leaves

Folk medicine has used preparations of guava leaves to manage diarrhea and to treat rheumatism, diabetes, cough, and many more disorders. (1)

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This article will take an in-depth look at the uses and benefits of guava leaves for health.

1. Aids in the management of diarrhea

Untreated and unmanaged diarrhea can be potentially life-threatening, especially in young children. Animal studies have found guava leaves can be useful in preventing infectious diarrhea by reducing its frequency and duration. (2)

A clinical trial in India also found a decoction of 14 guava leaves as a safe treatment for diarrhea in adults while also protecting the diversity of gut microorganisms that are normally destroyed by medication prescribed for diarrhea. (3)

2. Manages diabetes

Animal studies have also found guava leaf extract to lower the blood sugar levels and cholesterol levels associated with type 2 diabetes. Similar results were also observed in humans with no side effects. (4)

3. Reduces the risk of blood clots

Blood clots are a major risk for deaths associated with heart diseases. Clots can travel through the blood vessels and reach the heart, causing heart attacks.

Young guava leaves have been found to reduce the formation of blood clots and reduce the risk of heart disease. (1)

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4. Has anti-obesity properties

intake of guava leaf extract can help reduce your weight and obesity

Guava leaf extract also inhibits the formation of new fat cells and increases the amount of fat that is used for energy. Both of these functions are used to reduce weight gain. (5)

It also increases the activity of insulin, increasing the uptake of glucose by fat cells and thus improving the outcome of diabetes. (5)

5. Protects the liver

Guava leaves also play a role in protecting the liver from changes and damage due to diabetes. They can reduce the risk of developing a fatty liver while also managing insulin resistance, promoting the uptake of glucose and preventing spikes in blood sugar levels. (6)

6. Promotes oral health

Guava leaves have strong antimicrobial properties and can offer protection against bacteria that cause dental caries and gum diseases. In certain parts of India, young leaves are used to treat toothaches and mouth ulcers. (7)

This has been proven by studies where extracts of guava leaves were found effective against the formation of plaque and dental caries. (7)

7. May offer protection against cancer

Guava leaf extracts contain many bioactive compounds that can also offer protection against cancers.

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Lab studies have shown that extracts of guava leaf can inhibit the growth and spread of various types of cancer cells including lung cancer, colorectal carcinoma, myeloid leukemia, squamous cell carcinoma, cervical cancer, and gastric cancer. (8)

More extensive human trials are needed to establish evidence.

How to Consume

how to consume guava leaves?

About 10–14 guava leaves can be eaten daily with no side effects. You can either prepare tea or use them in your cooking.

For medicinal use, you can prepare decoctions (by boiling in water) or consume the young leaves raw.

How Many Guava Leaves can I Give My Child for Diarrhea?

Boil 5–7 young guava leaves in water for 10 minutes. Let the water cool down to room temperature, and give it to your child to drink.

Final Word

Guava leaves are rich in polyphenols that have a lot of health benefits. They can manage blood sugar levels and blood cholesterol levels, thus lowering the risk of diabetes.

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They also protect the liver and can prevent obesity by reducing the number of fat cells and increasing their use of energy. In addition, their antimicrobial benefit can help against oral diseases.

The leaves can be safely consumed and are not poisonous to humans.

References
  1. Díaz-de-Cerio E, Verardo V, Gómez-Caravaca AM, Fernández-Gutiérrez A, Segura-Carretero A. Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade. Int J Mol Sci. 2017;18(4):897. Published 2017 Apr 24. doi:10.3390/ijms18040897.
  2. Gupta P, Birdi T. Psidium guajava leaf extract prevents intestinal colonization of Citrobacter rodentium in the mouse model. J Ayurveda Integr Med. 2015;6(1):50-52. doi:10.4103/0975-9476.146557.
  3. Birdi T, Krishnan GG, Kataria S, Gholkar M, Daswani P. A randomized open label efficacy clinical trial of oral guava leaf decoction in patients with acute infectious diarrhoea. J Ayurveda Integr Med. 2020;11(2):163-172. doi:10.1016/j.jaim.2020.04.001.
  4. Chu S, Zhang F, Wang H, et al. Aqueous Extract of Guava (Psidium guajava L.) Leaf Ameliorates Hyperglycemia by Promoting Hepatic Glycogen Synthesis and Modulating Gut Microbiota. Front Pharmacol. 2022;13:907702. Published 2022 Jun 1. doi:10.3389/fphar.2022.907702.
  5. Choi E, Baek S, Baek K, Kim HK. Psidium guajava L. leaf extract inhibits adipocyte differentiation and improves insulin sensitivity in 3T3-L1 cells. Nutr Res Pract. 2021;15(5):568-578. doi:10.4162/nrp.2021.15.5.568.
  6. Kumar M, Tomar M, Amarowicz R, et al. Guava (Psidium guajava L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities. Foods. 2021;10(4):752. Published 2021 Apr 1. doi:10.3390/foods10040752.
  7. Daswani PG, Gholkar MS, Birdi TJ. Psidium guajava: A Single Plant for Multiple Health Problems of Rural Indian Population. Pharmacogn Rev. 2017;11(22):167-174. doi:10.4103/phrev.phrev_17_17.
  8. Liu HC, Chiang CC, Lin CH, et al. Anti-cancer therapeutic benefit of red guava extracts as a potential therapy in combination with doxorubicin or targeted therapy for triple-negative breast cancer cells. Int J Med Sci. 2020;17(8):1015-1022. Published 2020 Apr 6. doi:10.7150/ijms.40131.
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