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Home > Skin & Beauty > Is Methyl Estradiolpropanoate Safe for Skin?

Is Methyl Estradiolpropanoate Safe for Skin?

August 24, 2023 - Updated on September 5, 2023
6 min read
By Sarita Sanke, MD | Dermatology

In this article:

  • Safety and Efficacy of Topical Methyl Estradiolpropanoate
  • Uses of Topical Methyl Estradiolpropanoate
  • Are There Any Side Effects of Using Methyl Estradiol Propanoate?
  • How Does Methyl Estradiolpropanoate Work in the Skin?
  • How to Use Methyl Estradiolpropanoate on the Skin
  • Most-Asked Questions
  • Final Word

In the pursuit of youthful and radiant skin, many women, especially after a certain age or upon reaching menopause, use skin care products containing various ingredients and compounds.

is methyl estradiol propanoate safe for skin

Menopause brings a decrease in estrogen, which is important for healthy skin. This decline in estrogen can lead to skin symptoms of aging. Unfortunately, existing treatments for estrogen-deficient skin have risks and side effects.

The good news is there is promising research on a new compound that can improve postmenopausal skin without the harmful effects. This compound, called methyl estradiolpropanoate (MEP), acts similarly to estrogen but is applied topically and does not have systemic side effects. It has the potential to benefit estrogen-deficient skin. (1)

According to many experts, methyl estradiolpropanoate is safe for the skin and is often recommended by dermatologists (upon consultation), specifically for postmenopausal women.

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This article will look into methyl estradiol propanoate, exploring its use, potential benefits, and safety considerations so you can make informed decisions about its use on your skin.

Safety and Efficacy of Topical Methyl Estradiolpropanoate

Methyl estradiolpropanoate (MEP) is a substance used in topical skin care products to improve the appearance of postmenopausal skin.

In one study, the application of topical methyl estradiolpropanoate was found to be safe and did not cause any significant side effects throughout the study period. This means that methyl estradiolpropanoate can be used on the skin without causing harm to the body. (1)

When it came to effectiveness, the study showed promising results. Women who used methyl estradiolpropanoate on their skin experienced positive changes in various skin conditions. These included a reduction in dryness, improved firmness, less thinning of the skin, and a brighter complexion.

These findings suggest that methyl estradiolpropanoate has the potential to be a safe and effective option for women looking to improve the appearance of their postmenopausal skin. (1)

Note: More research is needed to fully understand the long-term effects and overall effectiveness of methyl estradiolpropanoate in skin care products.

Uses of Topical Methyl Estradiolpropanoate

Methyl estradiolpropanoate can be useful for the skin in many ways.

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1. Alleviates menopause-related skin issues

Methyl estradiolpropanoate has shown effectiveness in addressing various skin issues associated with menopause, according to researchers. It can improve the skin’s texture, thickness, and integrity and reduce the appearance of wrinkles and sun damage.

By targeting the skin, methyl estradiolpropanoate helps reduce the visible signs of aging caused by hormonal changes during menopause.

Methyl estradiolpropanoate offers a localized and skin-specific approach without systemic effects, making it a potentially safe and effective alternative to hormone replacement therapy for managing facial aging in postmenopausal women. (1)(2)

2. Improves skin hydration

Methyl estradiol propanoate-based skin care products have been shown to significantly improve skin hydration.

In one study, all participants experienced a noticeable improvement in skin hydration after using a methyl estradiolpropanoate serum for 20 weeks. The skin became better moisturized and less dry. (2)

3. Enhances skin appearance

Studies have found that using products with methyl estradiolpropanoate can improve the appearance of the skin. It helps reduce signs of aging, makes the skin smoother, and enhances its tone and color.

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Applying methyl estradiolpropanoate directly to the skin has shown promise in increasing skin thickness and collagen levels. This can lead to an improved facial appearance and a reduction in wrinkles. (1)(2)

4. Rejuvenates the skin around the eyes

In one study, participants who used a methyl estradiol propanoate-containing eye cream observed a significant improvement in the appearance of their periorbital skin area (eye area). Clinicians noted an overall aesthetic improvement with an increase in satisfaction of the participants with the appearance of their eye area.

Furthermore, all the participants well tolerated the cream, and no significant side effects were reported. (3)

Are There Any Side Effects of Using Methyl Estradiol Propanoate?

Unlike estrogen, methyl estradiolpropanoate does not become active in the bloodstream and is eliminated from the body without causing any hormonal side effects. As a result, methyl estradiolpropanoate offers the benefits of estrogen-based products without the associated risks.

Researchers are working on making methyl estradiolpropanoate technology widely accessible as a safe and effective treatment option for improving the appearance and health of estrogen-deficient skin. (4)

How Does Methyl Estradiolpropanoate Work in the Skin?

Methyl estradiolpropanoate is nonhormonal and works by stimulating estrogen receptors. It tells your skin to make more collagen and elastin, which are like the building blocks that keep your skin firm and elastic.

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Methyl estradiolpropanoate also helps to hydrate the deeper layer of your skin called the dermis, making it plump and moisturized. (4)

How to Use Methyl Estradiolpropanoate on the Skin

To use topical methyl estradiol propanoate, follow these steps:

  • Cleanse your skin.
  • Apply a small amount of methyl estradiol propanoate. Massage it gently into your skin and allow it to be absorbed.
  • Protect your skin with sunscreen.

Note: Use methyl estradiolpropanoate regularly as part of your skin care routine for best results. Also, consult a skin care professional for personalized advice.

Most-Asked Questions

Can methyl estradiolpropanoate be used on all skin types?

Yes, methyl estradiolpropanoate is suitable for various skin types.

Can methyl estradiolpropanoate be used with other skin care products?

Yes, methyl estradiolpropanoate can be used in combination with other products.

How often should I use methyl estradiol propanoate?

Use methyl estradiolpropanoate regularly as part of your skin care routine.

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Can methyl estradiolpropanoate be used during pregnancy?

Consult a healthcare professional before using methyl estradiolpropanoate during pregnancy.

Can methyl estradiolpropanoate be used in the morning and evening?

Methyl estradiolpropanoate can be used both in the morning and evening.

How long does it take to see results with methyl estradiol propanoate?

Results may vary, but improvements can be seen in weeks or months.

Final Word

Methyl estradiolpropanoate is considered safe for skin use; it provides the benefits of estrogen without the associated risks.

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However, it is important to consult with a healthcare professional before using methyl estradiolpropanoate to ensure its suitability for your needs and to address any potential concerns or risks.

References
  1. Srinivasan, M., Sudheer, A. R., & Menon, V. P. (2007, March). Ferulic acid: Therapeutic potential through its antioxidant property. Journal of clinical biochemistry and nutrition. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2127228/
  2. JL;, C. (n.d.). Evaluation of efficacy of a skin care regimen containing methyl estradiolpropanoate (MEP) for treating estrogen deficient skin. Journal of drugs in dermatology : JDD. https://pubmed.ncbi.nlm.nih.gov/31860210/
  3. J;, C. J. (n.d.). An open-label study evaluating the periorbital skin rejuvenation efficacy of a cosmeceutical containing methyl estradiolpropanoate (MEP) in women with estrogen deficient skin (eds). Journal of drugs in dermatology : JDD. https://pubmed.ncbi.nlm.nih.gov/36342739/
  4. Walter, Z. (2019, August 1). New solution for estrogen-deficient skin. LiVDerm. https://www.livderm.org/new-solution-for-estrogen-deficient-skin/
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