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Home > Skin & Beauty > Fungal Infections > Candidiasis: Causes, Symptoms, Diagnosis, and Treatment

Candidiasis: Causes, Symptoms, Diagnosis, and Treatment

Updated on August 30, 2022
5 min read
By Sarita Sanke, MD | Dermatology

In this article:

  • Who Gets Candidiasis?
  • Types of Candidiasis
  • Causes of Candidiasis
  • Symptoms of Candidiasis
  • Treatment for Candida
  • Diagnosis of Candidiasis
  • Risk Factors and Complications
  • When to See a Doctor
  • Final Word

Candidiasis is the name of a common fungal infection caused by a type of yeast known as Candida. This yeast can be normally found on the skin’s surface and the mouth, nose, vagina, etc. (1)

candidiasis infection: causes, signs, and treatment

Candidiasis occurs when there is an overgrowth of this organism in the body or if it enters into the bloodstream and internal organs. (2)

Who Gets Candidiasis?

Candida is usually a part of the body’s natural flora and can be found on the skin. However, certain conditions along with lowered immunity can encourage this yeast to overgrow and cause fungal infections.

  • Metabolic diseases such as diabetes can affect your immune system and make you prone to developing candidiasis.
  • Compromised immunity due to immune disorders will also raise your chances of developing fungal infections.
  • Improper hygiene and excessive humidity can also cause fungal skin infections in people.

Types of Candidiasis

Here are some common types of candidiasis that can occur in the body:

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  1. Thrush: Oral or vaginal thrush is a common fungal infection caused by Candida albicans.
  2. Esophagitis: Yeast infections that affect the esophagus and cause digestive issues are referred to as esophagitis. This usually occurs due to an oral fungal infection. (3)(4)
  3. Cutaneous (skin) candidiasis: Yeast infections that occur in the skin folds are a common occurrence. The armpits and skin behind the knees, between the toes, etc., tend to get sweaty often and become a prime breeding ground for yeast. (5)
  4. Vaginal yeast infections: Vaginal yeast infections are also common among women. (6)
  5. Deep candidiasis: This condition occurs when candidiasis spreads to the bloodstream and internal organs. It is a rare condition that can cause sepsis and even death. (7)

Causes of Candidiasis

The main culprit behind candidiasis infections is usually Candida albicans, a type of yeast that is commonly present on the skin’s surface. However, other types of yeast such as Candida krusei and Candida glabrata can cause candidiasis as well. (8)

Lowered immunity due to diabetes, immune disorders, chemotherapy, etc., is a major cause of candidiasis.

Symptoms of Candidiasis

signs and symptoms of candidiasis infection

Here are some common symptoms of candidiasis infections:

  • Itching and irritation in the affected area
  • Pinkish red rash
  • Vaginal thrush, which can cause a cloudy white discharge from the vagina
  • Oral thrush, which can cause a white coating on the tongue and mouth and pain while eating
  • Fatigue
  • Bloating and digestive issues such as diarrhea or constipation

Treatment for Candida

The treatment for candidiasis varies, depending on the area affected: 

treatment for candidiasis infection
  • Thrush – Thrush is usually treated with antimicrobial mouthwashes (such as liquid nystatin), clotrimazole lozenges that dissolve in the mouth, or oral antifungal medicines such as fluconazole. (9)
  • Esophagitis – Candida esophagitis is treated with an oral antifungal medicine such as fluconazole, itraconazole, or voriconazole. (10)
  • Cutaneous candidiasis – Skin infections caused by Candida are the most common types of candidiasis. It is important to keep the area clean and dry for proper treatment. Treatment involves the use of topical antifungal formulations such as ointments and powders. In severe cases, oral antifungal medicines are also prescribed.
  • Vaginal yeast infections – Vaginal candidiasis or vaginal thrush is treated with vaginal antifungal creams and suppositories or oral antifungal medicines. (11)
  • Deep candidiasis – Deep candidiasis may require the use of intravenous antifungal drugs such as voriconazole or fluconazole. In some cases, doctors may administer caspofungin or micafungin intravenously instead.

Diagnosis of Candidiasis

Candidiasis can be diagnosed by a doctor in the following ways:

  • Oftentimes, doctors diagnose skin, oral, and vaginal yeast infections simply by observing the rash and asking about your symptoms.
  • In some cases, they may ask you to undergo a blood test or swab test to confirm the diagnosis.
  • Esophagitis caused by Candida is diagnosed through a procedure called endoscopy. Endoscopy involves the insertion of a tiny camera through a flexible tube into your food pipe. This allows the doctor to observe your esophagus and also collect a swab sample for testing. (12)

Risk Factors and Complications

The following groups are more prone to develop candidiasis than others:

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  • People who have undergone organ transplants
  • People with diabetes with very high uncontrolled blood sugar levels
  • People with a weakened immune system due to AIDS or other immunosuppressive disorders

Although yeast infections are usually minor and do not cause any major problems, certain cases of candidiasis can lead to serious and life-threatening complications. These include: (13)

  • Swelling or inflammation in vital organs, such as nephritis or meningitis
  • Abscess formation under the skin
  • Organ failure or transplant rejections in patients

When to See a Doctor

when to consult a doctor regarding candidiasis infection?

You can try over-the-counter antifungal ointments for relief from skin infections. However, if your condition does not seem to improve, you can consult a doctor for proper treatment.

What you may ask your doctor
  • How serious is this condition?
  • What can I do to prevent these infections?
  • What medications do I need to take?
What your doctor may ask you
  • How long have you had these symptoms?
  • Have you taken any antibiotics recently?
  • Have you ever had candidiasis before?
  • Are you sexually active?

Final Word

Candidiasis is a common infection and can be annoying but is usually not serious.

Preventive measures such as maintaining proper hygiene, controlling your blood sugar level if you have diabetes, and dietary changes can help get rid of minor infections. Consult your doctor for the right treatment plan.

Continue Reading Continue Reading6 Home Remedies for Candida Overgrowth
References
  1. R AN, Rafiq NB. Candidiasis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; May 30, 2022.
  2. Candida infections of the mouth, throat, and esophagus. Centers for Disease Control and Prevention. https://www.cdc.gov/fungal/diseases/candidiasis/thrush/index.html. Published February 25, 2021.
  3. Baumgardner DJ. Oral Fungal Microbiota: To Thrush and Beyond. J Patient Cent Res Rev. 2019;6(4):252-261. Published 2019 Oct 28. doi:10.17294/2330-0698.1705.
  4. Mohamed AA, Lu XL, Mounmin FA. Diagnosis and Treatment of Esophageal Candidiasis: Current Updates. Can J Gastroenterol Hepatol. 2019;2019:3585136. Published 2019 Oct 20. doi:10.1155/2019/3585136.
  5. Benitez Ojeda AB, Mendez MD. Diaper Dermatitis. [Updated 2022 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559067/.
  6. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Vaginal yeast infection (thrush): Overview. 2019 Jun 19. Available from: https://www.ncbi.nlm.nih.gov/books/NBK543220/.
  7. Talapko J, Juzbašić M, Matijević T, et al. Candida albicans-The Virulence Factors and Clinical Manifestations of Infection. J Fungi (Basel). 2021;7(2):79. Published 2021 Jan 22. doi:10.3390/jof7020079.
  8. Taverne-Ghadwal L, Kuhns M, Buhl T, et al. Epidemiology and Prevalence of Oral Candidiasis in HIV Patients From Chad in the Post-HAART Era. Front Microbiol. 2022;13:844069. Published 2022 Feb 17. doi:10.3389/fmicb.2022.844069.
  9. Quindós G, Gil-Alonso S, Marcos-Arias C, et al. Therapeutic tools for oral candidiasis: Current and new antifungal drugs. Med Oral Patol Oral Cir Bucal. 2019;24(2):e172-e180. Published 2019 Mar 1. doi:10.4317/medoral.22978.
  10. Mohamed AA, Lu XL, Mounmin FA. Diagnosis and Treatment of Esophageal Candidiasis: Current Updates. Can J Gastroenterol Hepatol. 2019;2019:3585136. Published 2019 Oct 20. doi:10.1155/2019/3585136.
  11. Vaginal candidiasis – statpearls – NCBI bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK459317/.
  12. Robertson KD, Nagra N, Mehta D. Esophageal Candidiasis. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537268/.
  13. Badiee P, Hashemizadeh Z. Opportunistic invasive fungal infections: diagnosis & clinical management. Indian J Med Res. 2014;139(2):195-204.
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